２０２１

２０２１年
1. 原著論文
1.    Sho Saito, Kayoko Hayakawa, Shinya Tsuzuki, Masahiro Ishikane, Maki Nagashima, KazuhisaMezaki, Yuko Sugiki, Taichi Tajima, Nobuaki Matsunaga, Satoshi Ide, Noriko Kinoshita, YoshikiKusama, Yumiko Fujitomo, Takato Nakamoto, Yuta Toda, Mitsuo Kaku, Eiichi N Kodama, NorioOhmagari. The impact of the clinical outcomes and risk factors of patients with IMP-typecarbapenemase-producing carbapenem-resistant Enterobacteriaceae in Japan: A matched case-case-control study.Antimicrobial Agents and Chemotherapy65:e01483-20. doi: 10.1128/AAC.01483-20.　DOI: 10.1128/AAC.01483-20

2.    Shin-ichiro Hattori, Nobuyo Higashi-Kuwata, Hironori Hayashi, Srinivasa Allu, JakkaRaghavaiah, Haydar Bulut, Debananda Das, Brandon Anson, Emma Lendy, Yuki Takamatsu,Nobutoki Takamune, Naoki Kishimoto, Kazutaka Murayama, Kazuya Hasegawa, Mi Li, David Davis,Eiichi Kodama, Robert Yarchoan, Alexander Wlodawer, Shogo Misumi, Andrew Mesecar, ArunGhosh, and Hiroaki Mitsuya. A small compound with an indole moiety inhibits the main protease ofSARS-CoV-2 and blocks virus replication.Nature Communications12:668. doi: 10.1038/s41467-021-20900-6.

３．Atsushi Hozawa, Kozo Tanno, Naoki Nakaya1, Tomohiro Nakamura, Naho Tsuchiya, TakumiHirata, Akira Narita, Mana Kogure, Kotaro Nochioka, Ryohei Sasaki, Nobuyuki Takanashi, KotaroOtsuka, Kiyomi Sakata, Shinichi Kuriyama, Masahiro Kikuya, Osamu Tanabe, Junichi Sugawara,Kichiya Suzuki, Yoichi Suzuki, Eiichi N Kodama, Nobuo Fuse, Hideyasu Kiyomoto, Hiroaki Tomita,Akira Uruno, Yohei Hamanaka, Hirohito Metoki, Mami Ishikuro, Taku Obara, Tomoko Kobayashi,Kazuyuki Kitatani, Takako Takai-Igarashi, Soichi Ogishima, Mamoru Satoh, Hideki Ohmomo, AkitoTsuboi, Shinichi Egawa, Tadashi Ishii, Kiyoshi Ito, Sadayoshi Ito, Yasuyuki Taki, Naoko Minegishi,Naoto Ishii, Masao Nagasaki, Kazuhiko Igarashi, Seizo Koshiba, Ritsuko Shimizu, Gen Tamiya,Keiko Nakayama, Hozumi Motohashi, Jun Yasuda, Atsushi Shimizu, Tsuyoshi Hachiya, Yuh Shiwa,Teiji Tominaga, Hiroshi Tanaka, Kotaro Oyama, Ryoichi Tanaka, Hiroshi Kawame, AkimuneFukushima, Yasushi Ishigaki, Tomoharu Tokutomi, Noriko Osumi, Tadao Kobayashi, Fuji Nagami,Hiroaki Hashizume, Tomohiro Arai, Yoshio Kawaguchi, Shinichi Higuchi, Masaki Sakaida, RyujinEndo, Satoshi Nishizuka, Ichiro Tsuji, Jiro Hitomi, Motoyuki Nakamura, Kuniaki Ogasawara, NobuoYaegashi, Kengo Kinoshita, Shigeo Kure, Akio Sakai, Seiichiro Kobayashi, Kenji Sobue, MakotoSasaki, Masayuki Yamamoto. Study Profile of The Tohoku Medical Megabank Community-BasedCohort Study.Journal of Epidemiology 31:65-76. 2020 doi:10.2188/jea.JE20190271

４．Radhika Biyania, Kirti Sharmab, Kenji Kojima, Madhu Biyani, Kevin Maafu Juma, ItaruYanagihara, Shinsuke Fujiwara, Eiichi Kodama, Yuzuru Takamura, Masahiro Takagi, KiyoshiYasukawa, and Manish Biyani. Development of robust isothermal RNA amplification assay for lab-free testing of RNA viruses.Scientific Reports11, Article number: 15997, 2021
　　　新たなDNA合成酵素を用いてPCRの感度に匹敵する等温遺伝子増幅を可能としています。
　　　操作は新型コロナウイルスのようなRNAであってもワンステップで行うことができ、検出も
　　　インフルエンザの抗原検査のようにクロマト法を応用し、特別な機器を使わずに目視で行える
　　　画期的な方法です。

５．Masato Takase, Tomohiro Nakamura, Naho Tsuchiya, Mana Kogure, Fumi Itabashi, AkiraNarita, Takumi Hirata, Naoki Nakaya, Yohei Hamanaka, Junichi Sugawara, Kichiya Suzuki, NobuoFuse, Akira Uruno, Eiichi N Kodama, Shinichi Kuriyama, Ichiro Tsuji, Shigeo Kure, and AtsushiHozawa.  Association between the combination of fat mass index and fat free mass index withhypertension: The Tohoku Medical Megabank Community-based Cohort Study.Clinical andExperimental Hypertension43:610-621, 2021. doi: 10.1080/10641963.2021.1925681

６．Mitsuhiro Yamada, Ikuko N. Motoike, Kaname Kojima, Nobuo Fuse, Atsushi Hozawa, ShinichiKuriyama, Fumiki Katsuoka, Shu Tadaka, Matsuyuki Shirota, Miyuki Sakurai, Tomohiro Nakamura,Yohei Hamanaka, Kichiya Suzuki, Junichi Sugawara, Soichi Ogishima, Akira Uruno, Eiichi N.Kodama, Naoya Fujino, Tadahisa Numakura, Tomohiro Ichikawa, Ayumi Mitsune, Takashi Ohe,Kengo Kinoshita, Masakazu Ichinose, Hisatoshi Sugiura and Masayuki Yamamoto. Genetic loci forlung function in Japanese adults with adjustment for exhaled nitric oxide levels as airwayinflammation indicator.　Communications Biology4: 1288, 2021 　doi: 10.1038/s42003-021-02813-8

７．Soichi Ogishima, Satoshi Nagaie, Satoshi Mizuno, Ryosuke Ishiwata, Keita Iida, KazuroShimokawa, Takako Takai-Igarashi, Naoki Nakamura, Sachiko Nagase, Tomohiro Nakamura, NahoTsuchiya, Naoki Nakaya, Keiko Murakami, Fumihiko Ueno, Tomomi Onuma, Mami Ishikuro, TakuObara, Shunji Mugikura, Hiroaki Tomita, Akira Uruno, Tomoko Kobayashi, Akito Tsuboi, ShuTadaka, Fumiki Katsuoka, Akira Narita, Mika Sakurai, Satoshi Makino, Gen Tamiya, Yuichi Aoki,Ritsuko Shimizu, Ikuko N. Motoike, Seizo Koshiba, Naoko Minegishi, Kazuki Kumada, TakahiroNobukuni, Kichiya Suzuki, Inaho Danjoh, Fuji Nagami, Kozo Tanno, Hideki Ohmomo, Koichi Asahi,Atsushi Shimizu, Atsushi Hozawa, Shinichi Kuriyama, the Tohoku Medical Megabank Project StudyGroup, Nobuo Fuse, Teiji Tominaga, Shigeo Kure, Nobuo Yaegashi, Kengo Kinoshita, MakotoSasaki, Hiroshi Tanaka & Masayuki Yamamoto. dbTMM: an integrated database of large-scalecohort, genome and clinical data for the Tohoku Medical Megabank Project　Human GenomeVariation8:44, 2021 doi:10.1038/s41439-021-00175-5

2. 総説

3. 学会発表
1.　今年もできないかも・・・。

その他の業績

1. プレスリリース
　１．　新聞報道：　夕刊フジ

２．招待講演関連
　１．　COVID-19のこれまでとこれから　第35回宮城県臨床細胞学会　2月7日　Web開催
　２．　COVID-19について　公立藤田総合病院　感染対策セミナー　2月17日　福島県伊達市


2021.12.31:うさぎ小屋更新
2021.9.15:  論文（Sci Repなど＃4と#5）を更新しました
2021.4.17:  うさぎ小屋更新
2021.3.27:  論文・学会発表・講演・映像（外部サイト）を更新しました
2021.2.11:  論文・学会発表を更新しました